Artificial Inclusion Bodies for Clinical Development
نویسندگان
چکیده
منابع مشابه
Inclusion bodies in trachoma.
THE epithelial-cell inclusion, which is characteristically found in the early stages of trachoma was first described by Halberstaedter and Prowazek (1907). Since that time, a considerable literature concerning the nature of these bodies has accumulated. It is generally conceded that they consist of virus particles together with material elaborated by the virus and/or produced by the parasitized...
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The formation of inclusion bodies (IBs) constitute a frequent event during the production of heterologous proteins in bacterial hosts. Although the mechanisms leading to their formation are not completely understood, empirical data have been exploited trying to predict the aggregation propensity of specific proteins while a great number of strategies have been developed to avoid the generation ...
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In the last decades, the understanding of inclusion body biology and consequently, of their properties and potential biotechnological applications have dramatically changed. Therefore, the development of new purification protocols aimed to preserve those properties is becoming a pushing demand.
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THE first description of the inclusion bodies of trachoma was made by Halberstaedter and von Prowazek following the examination of Giemsa-stained scrapings from the conjunctivae of baboons which had been inoculated with secretions from trachomatous patients (cf. Julianelle, 1938). Since then Giemsa and its modifications have held prime place as a means of demonstrating these structures and this...
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included. References 1. Almeida A, Roberts I. Bone involvement in sickle cell disease. Br J Haematol 2005;129:482-490. 2. Booth C, Inusa B, Obaro SK. Infection in sickle cell disease: a review. Int J Infect Dis 2010;14:e2-e12. 3. Atkins BL, Price EH, Tillyer L, Novelli V, Evans J. Salmonella osteomyelitis in sickle cell disease children in the East End of London. J Infect 1997;34:133-138. 4. Bu...
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ژورنال
عنوان ژورنال: Advanced Science
سال: 2019
ISSN: 2198-3844,2198-3844
DOI: 10.1002/advs.201902420